Table 2.
Secondary Efficacy End Points: Mean Change in Outcome from Baseline to 2 months
Outcome | Waitlist (n=12)
|
SKY (ITT sample, n = 13)
|
SKY (Completer sample, n=11)
|
||||
---|---|---|---|---|---|---|---|
Change From Baseline | Change From Baseline | Difference From Waitlist Control in Change from Baseline
|
Change From Baseline | Difference From Waitlist Control in Change from Baseline
|
|||
Mean (SE) | Mean (SE) | Mean (95% CI) | P Value | Mean (SE) | Mean (95% CI) | P Value | |
Scale | |||||||
BDI, total score | −1.75 (2.56) | −17.23 (2.70) | 15.48 (−8.34 to −22.62) | 0.0101 | −20.36 (2.76) | 18.61 (−11.81 to −25.42 | 0.0043 |
BAI, total score | −.25 (1.48) | −5.44 (1.60) | −5.19 (−0.93 to −9.34) | 0.0097 | −6.48(1.75) | −6.23 (−1.39 to −11.07) | 0.0005 |
HDRS-17, total score | .50 (1.87) | −9.77 (1.90) | 10.27 (−5.04 to −15.50) | 0.0032 | −11.55 (2.00) | 12.05 (−6.71 to −17.38) | 0.0014 |
HDRS responders (%)a | 8.33% | 46.15% | 0.0730 | 54.54% | 0.0271 | ||
HDRS remitters (%)b | 8.33% | 30.77% | 0.3217 | 36.36% | 0.1550 |
Defined as patients having > 50% reduction from baseline HDRS-17 total score.
Defined as patients with HDRS-17 total score ≤ 7 and > 50% reduction in HDRS-17 total score from baseline.
Abbreviations: SKY = Sudarshan Kriya Yoga, ITT= intent-to-treat, HDRS-17 = 17-item Hamilton Depression Rating Scale, BDI = Beck Depression Inventory, BAI = Beck Anxiety Inventory