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. Author manuscript; available in PMC: 2017 Jan 28.
Published in final edited form as: J Clin Psychiatry. 2017 Jan;78(1):e59–e63. doi: 10.4088/JCP.16m10819

Table 2.

Secondary Efficacy End Points: Mean Change in Outcome from Baseline to 2 months

Outcome Waitlist (n=12)
SKY (ITT sample, n = 13)
SKY (Completer sample, n=11)
Change From Baseline Change From Baseline Difference From Waitlist Control in Change from Baseline
Change From Baseline Difference From Waitlist Control in Change from Baseline
Mean (SE) Mean (SE) Mean (95% CI) P Value Mean (SE) Mean (95% CI) P Value
Scale
 BDI, total score −1.75 (2.56) −17.23 (2.70) 15.48 (−8.34 to −22.62) 0.0101 −20.36 (2.76) 18.61 (−11.81 to −25.42 0.0043
 BAI, total score −.25 (1.48) −5.44 (1.60) −5.19 (−0.93 to −9.34) 0.0097 −6.48(1.75) −6.23 (−1.39 to −11.07) 0.0005
 HDRS-17, total score .50 (1.87) −9.77 (1.90) 10.27 (−5.04 to −15.50) 0.0032 −11.55 (2.00) 12.05 (−6.71 to −17.38) 0.0014
 HDRS responders (%)a 8.33% 46.15% 0.0730 54.54% 0.0271
 HDRS remitters (%)b 8.33% 30.77% 0.3217 36.36% 0.1550
a

Defined as patients having > 50% reduction from baseline HDRS-17 total score.

b

Defined as patients with HDRS-17 total score ≤ 7 and > 50% reduction in HDRS-17 total score from baseline.

Abbreviations: SKY = Sudarshan Kriya Yoga, ITT= intent-to-treat, HDRS-17 = 17-item Hamilton Depression Rating Scale, BDI = Beck Depression Inventory, BAI = Beck Anxiety Inventory