Table 2.

HAQL Adults - Known-groups validity for the proposed score (significant results are given in boldface)

HAQL dimensions	Disease statusa HD N = 8 ARM N = 60	Clinical status
		Autonomy statusa Usual A. N = 56 Lower A. N = 9	Soilingb Grade 0 N = 33 Grade 1 N = 24 Grade 2 N = 4 Grade 3 N = 3	Constipationb Grade 0 N = 36 Grade 1 N = 7 Grade 2 N = 6 Grade 3 N = 7	Voluntary bowel movementsb Grade 0 N = 30 Grade 1 N = 18 Grade 2 N = 9
Overall scale	621 ± 135 p = 0.55	621 ± 135 p = 0.27	Grade 0: 706 ± 80 Grade 1: 594 ± 129 Grade 2 or 3: 473 ± 112 p  < 0.0001	Grade 0 or 1 or 2: 639 ± 135 Grade 3: 462 ± 136 p  = 0.0121	Grade 0: 691 ± 103 Grade 1 or 2: 544 ± 142 p  = 0.0005
1- Laxative Diet	86 ± 24 p = 0.32	Usual A.: 83 ± 26 Lower A.: 98 ± 6 p  = 0.0004	86 ± 24 p = 0.12	Grade 0: 92 ± 18 Grade 1 or 2 or 3: 69 ± 30 p  = 0.0025	86 ± 24 p = 0.69
2- Presence of Diarrhea	78 ± 23 p = 0.34	78 ± 23 p = 0.85	Grade 0 : 88 ± 16 Grade 1: 76 ± 21 Grade 2 or 3: 57 ± 31 p  = 0.0021	78 ± 23 p = 0.80	Grade 0: 90 ± 13 Grade 1: 73 ± 17 Grade 2: 35 ± 29 p  < 0.0001
3- Fecal Continence	83 ± 22 p = 0.15	83 ± 22 p = 0.81	Grade 0: 97 ± 7 Grade 1: 82 ± 16 Grade 2 or 3: 47 ± 27 p  < 0.0001	83 ± 22 p = 0.57	Grade 0: 94 ± 12 Grade 1 or 2: 72 ± 21 p  < 0.0001
4- Urinary Continence	91 ± 19 p = 0.93	91 ± 19 p = 0.19	91 ± 19 p = 0.24	91 ± 19 p = 0.15	91 ± 19 p = 0.31
5- Social Functioning	78 ± 30 p = 0.83	78 ± 30 p = 0.11	Grade 0 or 1: 85 ± 25 Grade 2 or 3: 29 ± 25 p  < 0.0001	78 ± 30 p = 0.06	Grade 0: 91 ± 15 Grade 1 or 2: 62 ± 38 p  = 0.0028
6- Emotional Functioning and Body Image	64 ± 28 p = 0.50	Usual A.: 68 ± 26 Lower A.: 39 ± 27 p  = 0.0128	Grade 0: 78 ± 22 Grade 1: 58 ± 26 Grade 2 or 3: 25 ± 17 p  < 0.0001	64 ± 28 p = 0.12	Grade 0: 78 ± 21 Grade 1 or 2: 54 ± 29 p  = 0.0048
7- Physical symptoms	61 ± 24 p = 0.21	Usual A.: 64 ± 24 Lower A.: 47 ± 19 p  = 0.0441	Grade 0 : 72 ± 20 Grade 1: 56 ± 23 Grade 2 or 3: 33 ± 20 p  = 0.0001	Grade 0: 69 ± 25 Grade 1 or 2 or 3: 47 ± 20 p  = 0.0043	Grade 0: 72 ± 21 Grade 1 or 2: 53 ± 23 p  = 0.0127
8- Sexual functioning	81 ± 30 p = 0.80	81 ± 30 p = 0.22	Grade 0: 94 ± 15 Grade 1: 70 ± 36 Grade 2 or 3: 47 ± 27 p  = 0.0003	Grade 0: 87 ± 24 Grade 1 or 2 or 3: 67 ± 36 p  = 0.0320	81 ± 30 p = 0.19

^aStudent’s t-test, ^bAnova with post hoc pairwise Student’s t-tests