Table 2.
Plasma metabolite measurements *p < 0.05, **p < 0.01, ***p < 0.001. Data are presented as mean ± SEM
| Metabolite | Female | Male | 2-Way ANOVA Statistics | ||
|---|---|---|---|---|---|
| Sham | VSG | Sham | VSG | ||
| Triglycerides (mg/dl) | 339 ± 44 | 107 ± 21 | 439 ± 55 | 153 ± 27 | p (surgery) < 0.05 |
| Cholesterol (mg/dl) | 91 ± 4 | 87 ± 3 | 71 ± 4 | 62 ± 5 | p (sex) < 0.001 |
| β-Hydroxybutyrate (ng/ml) | 1.5 ± 0.1 | 1.5 ± 0.1 | 1.9 ± 0.1 | 1.7 ± 0.2 | NS |
| NEFA (mEq/L) | 1.8 ± 0.1 | 1.6 ± 0.1 | 2.3 ± 0.1 | 1.9 ± 0.1 | p (sex) < 0.001; p (surgery) < 0.01 |
| Total bile acids (μM/L) | 23 ± 3 | 93 ± 19 | 13 ± 5 | 45 ± 9 | p (sex) < 0.001; p (surgery) < 0.05 |
| Fat absorption (%) | 93 ± 2 | 82 ± 5 | 90 ± 4 | 82 ± 3 | p (surgery) < 0.01 |
| Estradiol (pg/ml) | 70 ± 11 | 39 ± 4 | 28 ± 2 | 20 ± 3 | p (sex) < 0.001; p (surgery) < 0.01 |
| Progesterone (ng/ml) | 6.4 ± 1.5 | 4.9 ± 0.6 | ND | ND | NS |