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Genotypic and allelic frequencies of Arg389Gly ADRB1 and Trp64Arg ADRB3 polymorphisms
| Polymorphism | Non-obese n = 698 |
Obese n = 348 |
P |
|---|---|---|---|
| Arg389Gly ADRB1 (rs1801253) | |||
| Arg/Arg | 549 (78.7%) | 256 (73.6%) | 0.08 |
| Arg/Gly | 132 (18.9%) | 86 (24.7%) | |
| Gly/Gly | 17 (2.4%) | 6 (1.7%) | |
| Alleles | |||
| Arg | 88.3% | 86.0% | 0.33 |
| Gly | 11.7% | 14.0% | |
| trp64Arg ADRB3 (rs4994) | |||
| Trp/Trp | 467 (66.9%) | 235 (67.5%) | 0.98 |
| Trp/Arg | 202 (28.9%) | 99 (28.5%) | |
| Arg/Arg | 29 (4.2%) | 14 (4.0%) | |
| Alleles | |||
| Trp | 82.1% | 82.12% | 0.99 |
| Arg | 17.9% | 17.88% | |
