Table I. (online only). Volumes of discrete brain regions according to group (N = 61).

Discrete brain region (mL)*	Cardiac (N = 48)	Control (N = 13)	P value†
Cerebrum
Cerebral white matter
Right cerebral white matter	116.9 ± 14.0	137.6 ± 16.0	<0.001
Left cerebral white matter	114.4 ± 14.4	133.4 ± 16.4	<0.001
Cerebral gray matter
Right frontal	53.5 ± 6.0	55.9 ± 7.0	0.11
Left frontal	53.3 ± 6.4	54.7 ± 7.5	0.38
Right perisylvian	11.7 ± 1.3	11.3 ± 1.3	0.24
Left perisylvian	11.7 ± 1.3	11.5 ± 1.2	0.57
Right parietal	49.6 ± 5.2	50.4 ± 4.7	0.49
Left parietal	49.2 ± 5.1	51.4 ± 5.9	0.12
Subcortical gray matter
Right thalamus	6.1 ± 0.5	5.7 ± 0.5	0.02
Left thalamus	6.2 ± 0.6	5.8 ± 0.4	0.007
Right caudate	2.9 ± 0.4	2.8 ± 0.4	0.40
Left caudate	2.7 ± 0.4	2.6 ± 0.3	0.31
Right putamen	3.8 ± 0.4	3.5 ± 0.4	0.01
Left putamen	3.9 ± 0.4	3.6 ± 0.4	0.05
Right pallidum	1.0 ± 0.1	1.0 ± 0.1	0.18
Left pallidum	1.1 ± 0.1	1.0 ± 0.2	0.23
Right hippocampus	2.8 ± 0.4	2.7 ± 0.3	0.12
Left hippocampus	2.7 ± 0.3	2.7 ± 0.3	0.79
Cerebellum
Cerebellar gray matter	83.3 ± 9.3	80.3 ± 9.2	0.15
Cerebellar white matter	14.5 ± 1.8	16.2 ± 2.8	<0.001
Vermis	8.0 ± 0.9	8.3 ± 1.0	0.18
Brainstem	11.2 ± 1.5	12.5 ± 2.0	0.003

^*Data are expressed as mean ± standard deviation.

^†P values were determined by linear regression adjusting for corrected chronological age at MRI and sex.