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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Magn Reson Med. 2016 Jul 28;78(1):97–106. doi: 10.1002/mrm.26348

Figure 1.

Figure 1

The pH dependence of CEST from iopamidol. The CEST spectra of iopamidol (inset) show changes in the CEST signals at 4.2 and 5.6 ppm over a range of pH 5.82 to 7.67. These experimental results were fit with the Bloch-McConnell equations to directly determine the pH-independent rate, k0, and pH-dependent rate, kb, of chemical exchange. CEST spectra are not shown for samples at pH 6.08 and 7.42, and for the sample at 39 mM at pH 6.72.