Table 5.
Overall mortality and frequency of CHDs and adjusted odds ratios for mortality compared to very/extremely premature infants without CHD (n=6973)
| Mortality | ||
|---|---|---|
|
| ||
| % died (95% CI) | Adjusted OR (95% CI) | |
| DORV (n=43, 0.6%) | 52.6 (29.8, 75.4) | 17.5 (6.0, 51.0) |
| Pulmonary atresia (n=35, 0.6%) | 30.3 (9.1, 51.5) | 13.2 (4.1, 42.3) |
| Non-HLHS single ventricle (n=48 0.7%) | 29 (13.1, 44.6) | 10.5 (4.7, 23.3) |
| HLHS (n=207, 3.0%) | 31.1 (23.9, 38.2) | 9.8 (6.4, 15.1) |
| Tetralogy of Fallot (n=96, 1.4%) | 26.4 (16.9, 35.9) | 7.1 (4.0, 12.4) |
| AV canal defect (n=42, 0.6%) | 25.5 (10.7, 40.3) | 6.6 (2.2, 19.8) |
| Coarctation (n=139, 2.0%) | 11.6 (4.3, 19.0) | 2.7 (1.2, 6.0) |
| VSD (n=1059, 15.2%) | 5.2 (3.4, 7.0) | 0.8 (0.5, 1.2) |
| Interrupted aortic arch (n=47, 0.7%) | 12.8 (1.0, 24.7) | 2.9 (0.8, 11.0) |
| ASD (n=4834, 69.3%) | 4.3 (3.5, 5.1) | 0.6 (0.5, 0.7) |
| Pulmonary stenosis (n=323, 4.6%) | 2.8 (0.8, 4.8) | 0.5 (0.2, 0.9) |
| Truncus arteriosus+ (n=22, 0.3%) | 67.4 (5.7, 59.4) | - |
| TAPVR+ (n=19, 0.3%) | 35.3 (5.7, 65.0) | - |
| Aortic stenosis+ (n=17, 0.2%) | 19.7 (0.0, 43.5) | - |
| TGA+ (n=24, 0.3%) | 19.0 (0.2, 37.8) | - |
| Ebstein anomaly+ (n=17, 0.2%) | 17.2 (13.0, 80.9) | - |
| Any severe defect (n=758, 10.9%) | 26.3 (22.7, 29.9) | 7.5 (5.9, 9.6) |
| No congenital heart defect | 5.3 (4.9, 5.8) | Reference |
*
Adjusted for GA, sex, race, SGA, Downs syndrome, hospital teaching status, year
+
Regression analysis was not performed for defects with sample size < 30