Table 2.

Multivariable Cox proportional hazard models assessing association of clinicopathologic parameters and PTEN/ERG status with biochemical recurrence in the combined African-American prostate cancer cohort (n = 222)

Variable	Multivariable HR (95% CI)	p value
Prostate-specific antigen	1.01 (0.99–1.04)	0.4
RP grade group
1 (GS 6)	1.00 (reference)
2 (GS 3 + 4)	2.16 (0.90–5.23)	0.086
3 (GS 4 + 3)	5.02 (1.92–13.1)	0.001
4 (GS 8)	5.45 (2.03–14.6)	0.001
5 (GS 9–10)	4.03 (1.39–11.9)	0.011
Pathologic stage
T2N0	1.00 (reference)
T3aN0	1.89 (1.03–3.57)	0.041
T3bN0	3.14 (1.56–6.30)	0.001
N1	6.64 (2.92–15.1)	<0.001
PTEN loss	2.25 (1.33–3.82)	0.003

HR = hazard ratio; CI = confidence interval; RP = radical prostatectomy; GS = Gleason score.