Figure 2. Fasting and 2-h plasma glucose levels in p.Arg684Ter allele carriers with T2D.

Homozygous TBC1D4 p.Arg684Ter variant carriers are shown in blue; homozygous p.Arg684Ter variant non-carriers and heterozygotes are shown in white. Data are from the 172 individuals with screen-detected T2D from the IHIT cohort for whom genotype information for this specific variant was available. T2D was diagnosed according to WHO 1999 criteria [7] based on fasting and 2-h plasma glucose values.