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. 2016 Aug 26;173(19):2859–2879. doi: 10.1111/bph.13562

Table 4.

ASCs or CM attenuates the expression of markers of tissue remodelling and inflammation in PF (Late phase)

Con (n = 5) B (n = 5) B + M (n = 4) BAD7 (n = 5) BCM7 (n = 5)
CTGF 1.12 ± 0.24 7.10 ± 1.28a 8.83 ± 1.65a 2.25 ± 0.25b 2.1 ± 0.25b , c
IL13 0.81 ± 0.09 4.68 ± 0.67a 5.67 ± 1.42a 1.01 ± 0.47b 1.81 ± 0.37b , c
MMP12 1.18 ± 0.27 34.3 ± 6.58a 43.83 ± 9.89a 10.9 ± 3.21b 20.46 ± 3.22b , c
TIMP1 1.05 ± 0.13 4.12 ± 0.81a 3.63 ± 0.36a 1.78 ± 0.33b 1.28 ± 0.06b , c
CCL2 1.12 ± 0.19 15.93 ± 3.05a 23.17 ± 5.65a 6.07 ± 0.96b 5.41 ± 1.32b , c
IL‐6 0.99 ± 0.81 4.68 ± 0.50a 5.88 ± 0.94a 1.70 ± 0.19b 1.43 ± 0.27b , c
COL1 0.90 ± 0.09 5.14 ± 1.48a 5.95 ± 1.49a 4.17 ± 0.82 5.32 ± 0.91
COL3 1.13 ± 0.20 4.19 ± 1.91 2.25 ± 0.49 1.45 ± 0.21 2.30 ± 0.32

Lung tissue harvested at the termination of the study was utilized for RT‐PCR analysis. Data presented are mean ± SEM, Con (n = 5), B (n = 5), B + M (n = 4), BAD7 (n = 5) and BCM7 (n = 5).

a

P ≤ 0.05, comparing B and B + M animals against the controls.

b

P ≤ 0.05, comparing BAD7 and BCM7 versus B.

c

P ≤ 0.05, comparing BCM7 versus B + M.