Table 4.
Con (n = 5) | B (n = 5) | B + M (n = 4) | BAD7 (n = 5) | BCM7 (n = 5) | |
---|---|---|---|---|---|
CTGF | 1.12 ± 0.24 | 7.10 ± 1.28a | 8.83 ± 1.65a | 2.25 ± 0.25b | 2.1 ± 0.25b , c |
IL13 | 0.81 ± 0.09 | 4.68 ± 0.67a | 5.67 ± 1.42a | 1.01 ± 0.47b | 1.81 ± 0.37b , c |
MMP12 | 1.18 ± 0.27 | 34.3 ± 6.58a | 43.83 ± 9.89a | 10.9 ± 3.21b | 20.46 ± 3.22b , c |
TIMP1 | 1.05 ± 0.13 | 4.12 ± 0.81a | 3.63 ± 0.36a | 1.78 ± 0.33b | 1.28 ± 0.06b , c |
CCL2 | 1.12 ± 0.19 | 15.93 ± 3.05a | 23.17 ± 5.65a | 6.07 ± 0.96b | 5.41 ± 1.32b , c |
IL‐6 | 0.99 ± 0.81 | 4.68 ± 0.50a | 5.88 ± 0.94a | 1.70 ± 0.19b | 1.43 ± 0.27b , c |
COL1 | 0.90 ± 0.09 | 5.14 ± 1.48a | 5.95 ± 1.49a | 4.17 ± 0.82 | 5.32 ± 0.91 |
COL3 | 1.13 ± 0.20 | 4.19 ± 1.91 | 2.25 ± 0.49 | 1.45 ± 0.21 | 2.30 ± 0.32 |
Lung tissue harvested at the termination of the study was utilized for RT‐PCR analysis. Data presented are mean ± SEM, Con (n = 5), B (n = 5), B + M (n = 4), BAD7 (n = 5) and BCM7 (n = 5).
P ≤ 0.05, comparing B and B + M animals against the controls.
P ≤ 0.05, comparing BAD7 and BCM7 versus B.
P ≤ 0.05, comparing BCM7 versus B + M.