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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Pediatr Nephrol. 2016 Jul 29;32(9):1481–1488. doi: 10.1007/s00467-016-3456-8

Figure 1. Proposed mechanisms for complex inheritance in SSNS.

Figure 1

Variation in genetic make-up can predispose to a cascade towards reversible podocyte injury phenotype by aberrant adaptive immune cells, stimulation by non-self antigens such as infective agents, or self/auto-antigens.