Table 2.
Candidate risk loci for SSNS
| Study population | Cohort size | Gene | References |
|---|---|---|---|
| French and German | 161 |
HLA-DQB HLA-DQA |
Konrad et al 1995 [58] |
| UK Caucasian | 40 |
HLA-DR7 HLA-DQW2 |
Clark et al 1990 [59] |
| US Caucasian | 32 | HLA-DQW2 | Lagueruela et al 1990 [60] |
| Japanese | 30 |
HLA-DQA1 HLA-DQB1 |
Kobayashi et al 1995 [62] |
| Chinese (Taiwan) | 59 |
HLA-DQB1 HLA-DR |
Huang et al 2009 [63] |
| South Asia | 76 |
HLA DRB1 HLA DQB1 |
Ramanathan et al 2015 [72] |
| South Asia USA white |
214 100 |
HLA-DQA1 PLCG2 |
Gbadegesin et al 2015 [65]* |
SSNS steroid sensitive nephrotic syndrome
*
Exome-wide study