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. 2017 Jan 17;18(3):636–646. doi: 10.1016/j.celrep.2016.12.070

Figure 3.

Figure 3

Effect of CES2 Expression on Metabolic Parameters in Mice

(A and B) Levels of human and mouse CES2 assessed by (A) qPCR and (B) western blot.

(C–E) Mesenteric (C) and gonadal (D) adipose tissue mass and liver-to-body weight ratio (E) from dissection of 4-hr-fasted mice on day 8 following viral injection.

(F) Serum ALT enzyme activity determined by enzymatic assay (n = 6–14).

(G) Representative images of H&E staining of formalin-fixed tissue (n = 6).

(H–M) Hepatic TAG (H), β-hydroxybutyrate (I), plasma TAG (J), hepatic cholesterol (K), plasma cholesterol (L), and plasma glucose (M) were determined by enzymatic end-point assays in plasma or hepatic extract (n = 12–17, unless otherwise noted). #Diet effect; §virus effect; xinteraction; ∗p < 0.05, Bonferroni post hoc test. Data are presented as mean ± SEM. See also Figure S1.