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. 2017 Jan 30;8:14. doi: 10.3389/fneur.2017.00014

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Copyright © 2017 Tamilia, Madsen, Grant, Pearl and Papadelis.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Output of the detection and localization of high-frequency oscillations (HFOs) with magnetoencephalography (MEG) in three patients with focal epilepsy. Upper panels: topographic maps of the HFO detection in the MEG sensors. Each sensor is represented by a dot whose color reflects the number of detected HFOs at the time of the HFOs in the highest rate channel. Lower panels: source localization (wavelet maximum entropy on the mean) of HFOs in the ripple band for the same three patients. Sources are displayed in a normalized color scale. The epileptogenic zone, determined based on the available clinical information, is delineated with a red square. For patient 1 and 2, the sources of HFOs were totally or partially concordant with the epileptogenic region, whereas for patient 3, they were discordant. Source: adapted from von Ellenrieder et al. (50).