Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A loss of SIR2 in calorie-restricted media affects multiple biological pathways consistent with the observed pleiotropic phenotype. A heatmap of transcriptomes shows upregulation of ribosome biogenesis genes, transcription and translation, and NAD-regulating genes, as well as downregulation of mating genes. Common gene ontology (GO) categories were also found from similar transcriptome mining in Saccharomyces cerevisiae and are highlighted with an asterisk.
