TABLE 3.
Diagnostic performance of antigens as determined by ROC curves
| Presentationa | Antigen | Cutoff | % sensitivity (95% CIb) | % specificity (95% CI) | % accuracy |
|---|---|---|---|---|---|
| ATL | rLB8E | 36.5 | 83.3 (72.1–91.4) | 83.3 (72.1–91.4) | 83.3 |
| rLb6H | 16.0 | 100.0 (94.7–100.0) | 98.5 (92.1–100.0) | 99.2 | |
| L. major-like | 10.0 | 91.2 (81.8–96.7) | 95.6 (87.6–99.1) | 91.1 | |
| VL | rLB8E | 39.1 | 95.4 (87.3–99.0) | 92.4 (83.2–97.5) | 93.1 |
| rLb6H | 6.1 | 89.4 (79.4–95.6) | 95.3 (86.9–99.0) | 92.3 |
a
Samples used in the calculation of the cutoff versus control samples from healthy individuals. ATL, American tegumentary leishmaniasis; VL, visceral leishmaniasis.
b
95% CI, 95% probability confidence interval.