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. 2017 Jan 25;55(2):574–584. doi: 10.1128/JCM.02087-16

TABLE 3.

Allelic diversity of mmpT5 among clinical isolates of M. intracellulare

mmpT5 position mmpT5 allelea
Nucleotide change Statusb Amino acid change
1.1 1.2 2.1 3.1 3.2 3.3 4.1 4.2 5.1 5.2 5.3 5.4 6.1 7.1 7.2 7.3 8.1
56 T G T56→G NS Ile19→Ser
67 G C G67→C NS Ala23→Pro
72 A G G G G G A72→G Syn Val24→Val
74 G C G74→C NS Arg25→Pro
104 T G T104→G NS Val35→Gly
129 A G G A129→G Syn Glu43→Glu
137 T G T137→G NS Val46→Gly
196/197 C C196_197→insCc FS Gly66→fs
311/312 C C C311_312→insC FS Pro104→fs
378 G A G378→A Syn Ala126→Ala
429 C T T T T C429→T Syn Val143→Val
450 C T C450→T Syn Pro150→Pro
471 G A A A A A A A A A G471→A Syn Leu157→Leu
484 G C G484→C NS Ala162→Pro
504 G G504→Z Syn Ser168→Ser
522 G A A A G522→A Syn Ala174→Ala
528 C T T T T T T T T T T T T T T C528→T Syn Gly176→Gly
529 G A A A A G529→A NS Glu177→Lys
582 G A A A G582→A Syn Ala194→Ala
a

• identical to allele 1.1 (mmpT5 sequence from M. intracellulare ATCC 13950T).

b

Syn, synonymous change; NS, nonsynonymous change; FS, frameshift mutation.

c

insC, insertion of C.