Smoothed connectivity profiles for glioma patients and healthy controls. In all panels, smoothed frequencies of occurrence according to subjects' individual connectivity values (y-axes) were determined for 100 equally spaced bins (x-axes), and depicted in black. Averaged distributions over the entire group are shown in red. (A) Depicts the frequency distribution (FD) of functional connectivity for glioma patients during task-state fMRI (n = 71). In (B), the FD of the healthy controls using task-state fMRI is shown. In (C), the FD of the resting-state data of the same healthy controls is depicted. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)