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Flagellin and LPS activate systemic and local inflammation. BALB/c mice (n = 5) were treated intraperitoneally with flagellin (5 μg) or LPS (5 μg) in PBS or with PBS alone. Blood and ileum were sampled 2 h posttreatment. IL-6 and CXCL2 levels were measured by ELISA in serum (A) and ileum homogenates (B). The data are shown as the means ± SD. Data from flagellin-treated and LPS-treated mice were compared in a Mann-Whitney test (*, P < 0.05; **, P < 0.01).
