Cells lacking AHR1 are defective in hyphal morphogenesis during phagocytosis. FITC-stained C. albicans wild-type, ahr1Δ, ahr1Δ stp2Δ, ahr1Δ+AHR1, and stp2Δ strains were cocultured with J774A.1 macrophages for 60 min. Nonphagocytosed fungal cells were stained with calcofluor white, and then the cocultures were fixed and imaged. The percentage of phagocytosed hyphae (A, B) and hyphal length (C, D) were scored as described in Materials and Methods. *, P < 0.05; **, P < 0.01; ***, P < 0.001.