Table 1. Characteristics of normal rats and cirrhotic rats with or without BT.
| Indexes | Normal | Without BT | BT |
|---|---|---|---|
| (n = 12) | (n = 12) | (n = 11) | |
| Total protein (g/dL) | 5.1 ± 0.3 | 5.0 ± 1.3 | 4.1 ± 0.6*,# |
| Albumin (g/dL) | 3.3 ± 0.2 | 2.6 ± 0.9** | 1.5 ± 0.4*,# |
| Globulin (g/dL) | 1.8 ± 1.5 | 2.5 ± 0.2** | 2.5 ± 0.1* |
| Albumin/Globulin | 1.9 ± 0.1 | 1.0 ± 0.3** | 0.7 ± 0.2*,# |
| ALT (U/L) | 49.6 ± 13.9 | 154.6 ± 34.6 | 228.3 ± 159.0* |
| AST (U/L) | 76.5 ± 11.2 | 318.9 ± 94.6 | 685.2 ± 670.8* |
| ALP (U/L) | 29 ± 32.6 | 165.7 ± 110.0** | 198.9 ± 113.4* |
| TBIL (μmol/L) | 1.8 ± 0.6 | 21.7 ± 15.1** | 27.7 ± 19.5* |
| DBIL (μmol/L) | 1.8 ± 0.6 | 18.9 ± 12.3** | 24.0 ± 16.3* |
| IBIL (μmol/L) | 0 ± 0.9 | 2.9 ± 3.0 | 3.7 ± 3.4* |
| GGT (U/L) | −2.9 + 1.4 | 16.3 ± 10** | 16.6 ± 14.6* |
| Initial body weight (g) | 212.5 ± 8.1 | 213.0 ± 5.6 | 213.6 ± 7.0 |
| Final body weight (g) | 469.5 ± 11.3 | 379.5 ± 17.1** | 346.2 ± 50.6*,# |
| Body weight increase (g) | 257.0 ± 10.1 | 166.6 ± 16.0** | 132.6 ± 46.7*,# |
| Spleen weight (g) | 0.9 ± 0.1 | 1.4 ± 0.3** | 1.7 ± 0.4*,# |
| Spleen weight/Final body weight (%) | 0.19 | 0.36 | 0.49 |
| Ascites amount (mL) | / | 16.2 ± 7.5 | 25.7 ± 5.4# |
| Ascites/Final body weight (mL/kg) | / | 43.1 ± 20.9 | 76.0 ± 21.0# |
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; GGT, gamma-glutamyl transpeptidase; TBIL, total bilirubin; DBIL, direct bilirubin; IBIL, indirect bilirubin; GGT, γ-glutamyl transpeptidase. The data are presented as the means ± SD. *P < 0.05, BT versus Normal; **P < 0.05, Without BT versus Normal; #P < 0.05, BT versus Without BT, one-way ANOVA.