Figure 5. Reduced CT-mediated T_H17 responses and IL-17A production in absence of IL-6.

(a) After immunization with intranasal CTO of 6 to 8- week-old WT or IL-6 deficient mice on the B6 background, total cell and inflammatory cell numbers were assessed in BAL fluid. (b) Representative and compiling flow cytometric analysis of IL-17A and IFN-γ production by CD4 T cells from lungs of WT and IL-6 deficient mice are depicted. Data are representative of four independent experiments (n = 5) and are presented as mean ± SEM.