Skip to main content
. 2017 Jan 30;7:41738. doi: 10.1038/srep41738

Figure 7. miR-143 mediates NO-induced apoptosis.

Figure 7

SH-SY5Y cells were transfected with miR-143 inhibitor (143i) or negative control (NC) inhibitor for 2 d, and treated with SNP (1 mM) for 16 h. (A) Cell viability was assessed by MTT assay, (D) cleaved PARP was detected with Western blotting, and (E) FACS analysis was conducted to evaluate the effect of miR-143 inhibitor on NO-induced apoptosis. (B and C) RBM3-overexpressing cells were transfected with miR-143 mimics (RBM + 143 m) or NC mimics for 2 d, and then treated with SNP for 16 h. (B) Cell viability was assessed by MTT assay, and (C) cleaved PARP was detected with Western blotting. The lower panels in C and D are histogram analysis for corresponding levels of cleaved PARP. *P < 0.05, **P < 0.01 and ***P < 0.001 versus control group.