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. 2016 Dec 5;114(4):E476–E485. doi: 10.1073/pnas.1618657114

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Fig. S9. — Comparison of Aβ42 and Aβ40 production by 10 γ-secretase variants containing either APH-1aL or APH-1b. (A) A plot of the total amount of Aβ42 and Aβ40 generated by γ-secretase variants containing either APH-1aL or APH-1b. (B) A plot of the total amount of Aβ42 and Aβ40 versus mean AAO for the APH-1b–containing γ-secretase variants. (C) The ratios of Aβ42 over Aβ40 produced by these γ-secretase variants. (D) A plot of the Aβ42/Aβ40 ratio versus mean AAO for the APH-1b–containing γ-secretase variants.