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. 2017 Jan 9;114(4):E524–E533. doi: 10.1073/pnas.1614336114

Fig. S2.

Fig. S2.

(A) Mean cumulative clinical EAE score from recombinant human MOG-immunized C57BL/6 WT and ALCAM KO mice. Data shown are the mean ± SEM of 42 WT and 45 ALCAM KO mice per group and are the cumulative clinical scores obtained in n = 3 independent experiments. AUC: WT, 54.88 ± 2.29; ALCAM KO, 64.07 ± 2.59. *P ≤ 0.05. (B) Percentage of CD4+ or CD8+ T lymphocytes isolated from the spleen and the LNs of ALCAM KO and WT mice expressing IFNγ and/or IL-17 at different time points post–MOG35–55 induction of active EAE. Data shown are the mean ± SEM of three animals per time point.