Table 3. Plasma lipids and atherosclerosis in LDLr−/− mice expressing human apoE3 or apoE4 fed a NC diet.
Male 3ko | Female 3ko | Male 4ko | Female 4ko | |
---|---|---|---|---|
Number | 11 | 12 | 12 | 12 |
TC (mg/dl) | 241 ± 18 | 386 ± 12 | 313 ± 25 | 427 ± 32 |
TG (mg/dl) | 109 ± 12 | 102 ± 6 | 225 ± 22 | 114 ± 2 |
Lesion size (103 μm2) | 13.4 ± 3.1 | 55.5 ± 7.2 | 12.0 ± 2.7 | 71.0 ± 14.4 |
Occlusion (%) | 1.3 ± 0.3 | 5.1 ± 0.5 | 1.0 ± 0.2 | 5.4 ± 0.8 |