Table 1.
Baseline characteristics of the Health ABC participants by leptin group
| Leptin Group | ||||
|---|---|---|---|---|
|
| ||||
| Characteristic | Low (n=479) | Middle (n=1915) | High (n=476) | P-Value* |
|
| ||||
| Age (mean, SD) | 73.8 (2.9) | 73.7 (2.9) | 73.2 (2.8) | < 0.01 |
| Black (%) | 36.7 | 37.7 | 56.1 | < 0.01 |
| Female (%) | 16.1 | 47.3 | 89.5 | < 0.01 |
| Education ≤ high school (%) | 54.4 | 56.6 | 64.1 | < 0.01 |
| Depression score ≥ 16 (%) | 3.8 | 6.1 | 5.3 | 0.31 |
| Body mass index, kg/m2 (mean, SD) | 23.3 (3.1) | 27.0 (4.0) | 31.1 (4.8) | < 0.01 |
| Total % body fat (mean, SD) | 25.3 (4.6) | 34.6 (5.8) | 43.0 (4.9) | <0.01 |
| Hypertension (%) | 38.7 | 50.8 | 60.9 | < 0.01 |
| Diabetes (%) | 10.5 | 15.4 | 18.2 | 0.02 |
| Myocardial infarction history (%) | 15.0 | 12.1 | 7.6 | <0.01 |
| Stroke/TIA history (%) | 7.0 | 7.9 | 5.1 | 0.25 |
| Number of days in hospital (%) | ||||
| 0–7 | 84.3 | 82.8 | 84.2 | 0.59 |
| >7 | 15.7 | 17.2 | 15.8 | |
| ApoE ε4 Carrier (%) | 28.5 | 28.7 | 26.5 | 0.50 |
| Baseline 3MS score (mean, sd) | 92.2 (7.4) | 93.0 (6.3) | 92.7 (6.3) | 0.31 |
*
P-value for trend.