TABLE 1.
Characteristics of blaOXA-48-like genes detected in Dutch freshwater and livestock, imported ornamental fish, and transport water
| Gene | No. of samples | Reference | Gene homology (%) | Amino acid differences | Accession no.b | Source (origin/no. of samples) |
|---|---|---|---|---|---|---|
| blaOXA-514 | 1 | A201G (from OXA-416) | KU866382 | Ornamental fish (Indonesia) | ||
| blaOXA-515 | 1 | G201S (from OXA-252) | KU866383 | Freshwater (Netherlands) | ||
| blaOXA-48 | 1 | KT265183 | 99 | KU820821 | Slaughter pig | |
| blaOXA-48b | 7 | JX644945 | 99–100 | KU820801 (S), KU820802 (S), KU820804 (S) | Freshwater (Netherlands) | |
| 69 | 99–100 | KU820811, KU820813, KU820814, KU820815, KU820816 | Ornamental fish (32) fish transport water (37) | |||
| 3 | 100 | KU820805 (S), KU820806 (S), KU820807 (S) | Broiler (2), veal calf (1) | |||
| blaOXA-181 | 3 | HM992946 | 100 | KU820809, KU820810, KU820803 (S) | Ornamental fish (Colombia, 2, Singapore, 1) | |
| blaOXA-199 | 1 | JN704570 | 99 | KU820808 | Ornamental fish (Congo) | |
| 1 | 100 | KU820819 | Freshwater (Netherlands) | |||
| blaOXA-252 | 1 | WP_037428895 | 100a | KU820800 (S) | Slaughter pig | |
| blaOXA-48 family | 2 | JX644945 | 99 | W222G, V232G | KU820818 | Slaughter pig |
| 99 | N179I | KU820820 | Broiler | |||
| Class D β-lactamase | 2 | JX644945 | 94 | V21E, N28T, A33T, T104A | KU820812, KU820817 | Fish transport water (Israel) |
a
Amino acid homology with OXA-252 derived from BLASTX alignment in GenBank, since no gene sequence for blaOXA-252 is available in GenBank, as of this writing.
b
Only representative sequences were deposited in GenBank; S, sequenced from Shewanella isolate (see also Table 2).