TABLE 2.
Source and isolatea | Species | Origin | Gene | MIC (mg/liter) forb: |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CTX | CTX + CLA | CAZ | CAZ + CLA | FEP | FOX | ETP | IPM | MEM | TRM | ||||
Environmental freshwater | |||||||||||||
W9 | S. xiamenensis | Netherlands | blaOXA-48b | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | 1 | 2 | 2 | 0.5 | 1 |
W13 | S. oneidensis | Netherlands | blaOXA-48b | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | 1 | >2 | 2 | 1 | ≤0.5 |
W14 | S. oneidensis | Netherlands | blaOXA-48b | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | 1 | 2 | 2 | 1 | ≤0.5 |
W15 | S. xiamenensis | Netherlands | blaOXA-48b | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | 1 | 2 | 2 | 1 | 1 |
W16 | S. oneidensis | Netherlands | blaOXA-48b | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | 1 | >2 | 2 | 0.5 | ≤0.5 |
W17 | Shewanella spp. | Netherlands | blaOXA-515c | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | ≤0.5 | 2 | 2 | 0.5 | ≤0.5 |
W21 | S. xiamenensis | Netherlands | blaOXA-48b | ≤0.25 | 0.25/4 | ≤0.25 | 0.25/4 | 0.12 | 2 | >2 | 4 | 4 | 4 |
Ornamental freshwater fish | |||||||||||||
10A | S. xiamenensis | Indonesia | blaOXA-514d | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | 2 | 1 | 1 | 0.5 | ≤0.5 |
13C | S. xiamenensis | Israel | blaOXA-48b | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | ≤0.5 | 2 | 2 | 1 | ≤0.5 |
25B | Shewanella spp. | Singapore | blaOXA-181e | ≤0.25 | 0.12/4 | ≤0.25 | ≤0.12/4 | 0.12 | 1 | 2 | 2 | 1 | ≤0.5 |
32B | S. xiamenensis | Indonesia | blaOXA-48b | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | 1 | 2 | 1 | 0.5 | ≤0.5 |
36B | S. xiamenensis | Singapore | blaOXA-48b | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | 2 | 2 | 1 | 0.5 | ≤0.5 |
39B | Shewanella spp. | Singapore | blaOXA-48b | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | 0.5 | 2 | 2 | 1 | 0.5 | 1 |
45B | Shewanella spp. | Thailand | blaOXA-48b | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | 1 | 2 | 1 | 0.5 | 1 |
F2.1-22 | S. xiamenensis | Indonesia | blaOXA-48b | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | 2 | >2 | 4 | 2 | 2 |
F2.1-24 | Shewanella spp. | Indonesia | blaOXA-48b | ≤0.25 | 0.25/4 | ≤0.25 | 0.5/4 | 0.12 | 2 | >2 | >16 | 8 | 4 |
F3.2 | Shewanella spp. | Indonesia | blaOXA-48b | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | 1 | >2 | 4 | 2 | ≤0.5 |
Slaughter pig | |||||||||||||
1553/2014 | S. xiamenensis | Netherlands | blaOXA-252f | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | 1 | 2 | 1 | 0.5 | ≤0.5 |
Broiler | |||||||||||||
780/2015 | S. xiamenensis | Netherlands | blaOXA-48b | ≤0.25 | ≤0.06/4 | 0.5 | ≤0.12/4 | ≤0.06 | 4 | 1 | 2 | 1 | 4 |
1206/2015 | S. xiamenensis | Netherlands | blaOXA-48b | ≤0.25 | ≤0.06/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | 1 | 2 | 1 | 0.5 | ≤0.5 |
Veal calf | |||||||||||||
77/2015 | S. oneidensis | Netherlands | blaOXA-48b | ≤0.25 | 0.12/4 | ≤0.25 | ≤0.12/4 | ≤0.06 | 1 | 2 | 2 | 1 | 1 |
Isolates were classified as non-wild type susceptible based on EUCAST ECOFFS (www.eucast.org).
CTX, cefotaxime; CLA, clavulanic acid; CAZ, ceftazidime; FEP, cefepime; FOX, cefoxitin; ETP, ertapenem; IPM, imipenem; MEM, meropenem; TRM, temocillin.
Accession no. KU866383.
Accession no. KU866382.
Accession no. KU820803.
Accession no. KU820800.