TABLE 1.
Arm (no. of subjects) | DRV dose | Mean ± SD (minimum, maximum) |
No. (%) |
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---|---|---|---|---|---|---|---|---|---|
Age (yr) | Wt (kg) | Ht (cm) | BMI (kg/m2) | Sex (male/female) | Race (White/black/Asian) | HCV genotype (1a/1b) | Cirrhosis diagnosis | ||
C (10) | QD | 55.0 ± 6.62 (44, 65) | 78.9 ± 13.6 (61, 103) | 174 ± 12.6 (155, 188) | 26.1 ± 3.1 (21, 31) | 8 (80)/2 (20) | 7 (70)/3 (30) | 9 (90)/1 (10) | 0 (0) |
D (12) | BID | 52.4 ± 11.3 (34, 68) | 82.4 ± 17.3 (59, 111) | 172 ± 8.9 (160, 188) | 27.9 ± 6.1 (22, 38) | 9 (75)/3 (25) | 5 (42)/6 (50)/1 (8) | 6 (50)/6 (50) | 3 (25) |
Total (22) | 53.6 ± 9.35 (34, 68) | 80.8 ± 15.5 (59, 111) | 173 ± 10.5 (155, 188) | 27.1 ± 5.0 (21, 38) | 17 (77)/5 (23) | 12 (54.5)/9 (41)/1 (4.5) | 15 (68)/7 (32) | 3 (13.6) |
SD, standard deviation; BMI, body mass index.