TABLE 3.
Susceptibility of M. bovis BCG strains to various fatty acids
| Fatty acid | MIC90a (mM) |
||
|---|---|---|---|
| BCG | BCG fadD2::kan | BCG fadD2::kan/pJT6a::fadD2 | |
| Acetate (C2:0) | 50 | 50 | 50 |
| Propionate (C3:0) | 50 | 12.5 | 25 |
| Butyrate (C4:0) | 50 | 6.25 | 25 |
| Valerate (C5:0) | 25 | 3.125 | 25 |
| Caprylate (C8:0) | 2 | 1 | 2 |
| Laurate (C12:0) | 0.5 | 0.25 | 0.5 |
| Palmitate (C16:0) | 0.5 | 0.5 | 0.5 |
| Oleate (C18:cis-9) | 1 | 0.5 | 1 |
a
The MIC90 was defined as the minimum concentration of fatty acid necessary for inhibition of at least 90% of the growth in standard medium without additional fatty acids.