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. 2017 Jan 24;61(2):e02130-16. doi: 10.1128/AAC.02130-16

TABLE 4.

Minimum concentrations of pantothenate necessary for antagonism of POA activity against Mycobacterium bovis BCG strains

Strain Characteristic Pantothenate MAC10a (μM)
M. bovis BCG Wild type 3.27
M. bovis BCG fadD2::kan/pJT6a Mutant with a transposon insertion disrupting fadD2 expression 13.1
M. bovis BCG fadD2::kan/pJT6a::fadD2 Complemented fadD2 disruption mutant 6.55
a

MAC10 was defined as the minimum concentration of the antagonistic metabolite necessary to permit at least 10% of the growth exhibited by the drug-free control culture in the presence of drug at two times the MIC90.