TABLE 3.

Results for samples with C_trough values of ≥1 mg/liter for the different population analysis sets

Wt band (kg)	Overall population		ANRS 12174 protocol dose populationa		WHO simulated populationa,b
	n obs.c	No. (%) of infants with a Ctrough of ≥1 mg/liter	n obs.	No. (%) of infants with a Ctrough of ≥1 mg/liter	n obs.	No. (%) of infants with a Ctrough of ≥1 mg/liter
<4	12	9 (75)	11	9 (82)	11	10 (91)
≥4	102	71 (70)	73	72 (99)	73	73 (100)

^aData for samples from infants that may have missed a dose at the sampling time were excluded.

^bData for the WHO simulated population are simulated concentrations that the 2016 WHO dosing guidelines would produce for HIV-1-infected children.

^cn obs., number of observations.