TABLE 2.
Organism | Time (h) | MIC (μg/ml)a |
||||
---|---|---|---|---|---|---|
Anid | Caspo | CD101 | 6 | AmpB | ||
Candida albicans ATCC 90028 | 24 | ≤0.015 | 0.06 | 0.03 | 0.03 | ≤0.06 |
48 | ≤0.015 | 0.06 | 0.03 | 0.03 | 0.125 | |
Candida glabrata ATCC 90030 | 24 | 0.03 | 0.125 | 0.03 | 0.03 | 0.06 |
48 | 0.03 | 0.125 | 0.03 | 0.03 | 0.25 | |
Candida guilliermondii ATCC 34134 | 24 | 1 | 0.25 | 0.5 | 0.5 | ≤0.06 |
48 | 2 | >16b | 2 | 1 | ≤0.06 | |
Candida krusei ATCC 14243 | 24 | 0.03 | 0.25 | 0.03 | 0.03 | 0.25 |
48 | 0.06 | 0.5 | 0.03 | 0.03 | 0.5 | |
Candida lusitaniae ATCC 34134 | 24 | 0.125 | 0.25 | 0.25 | 0.25 | ≤0.06 |
48 | 0.125 | 0.25 | 0.25 | 0.25 | ≤0.06 | |
Candida parapsilosis ATCC 22019 | 24 | 0.5 | 0.25 | 0.5 | 0.25 | 0.25 |
48 | 0.5 | 0.5 | 1 | 0.5 | 0.5 | |
Candida tropicalis ATCC 90874 | 24 | ≤0.015 | 0.06 | ≤0.015 | ≤0.015 | 0.25 |
48 | ≤0.015 | 0.06 | ≤0.015 | ≤0.015 | 0.25 |
AmpB, amphotericin B; Anid, anidulafungin; Caspo, caspofungin.
Reduced growth occurred, but the CLSI endpoint was not achieved.