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. 2017 Jan 24;61(2):e01541-16. doi: 10.1128/AAC.01541-16

TABLE 2.

MICs of CD101 and compound 6 with echinocandin and polyene comparators against Candida spp.

Organism Time (h) MIC (μg/ml)a
Anid Caspo CD101 6 AmpB
Candida albicans ATCC 90028 24 ≤0.015 0.06 0.03 0.03 ≤0.06
48 ≤0.015 0.06 0.03 0.03 0.125
Candida glabrata ATCC 90030 24 0.03 0.125 0.03 0.03 0.06
48 0.03 0.125 0.03 0.03 0.25
Candida guilliermondii ATCC 34134 24 1 0.25 0.5 0.5 ≤0.06
48 2 >16b 2 1 ≤0.06
Candida krusei ATCC 14243 24 0.03 0.25 0.03 0.03 0.25
48 0.06 0.5 0.03 0.03 0.5
Candida lusitaniae ATCC 34134 24 0.125 0.25 0.25 0.25 ≤0.06
48 0.125 0.25 0.25 0.25 ≤0.06
Candida parapsilosis ATCC 22019 24 0.5 0.25 0.5 0.25 0.25
48 0.5 0.5 1 0.5 0.5
Candida tropicalis ATCC 90874 24 ≤0.015 0.06 ≤0.015 ≤0.015 0.25
48 ≤0.015 0.06 ≤0.015 ≤0.015 0.25
a

AmpB, amphotericin B; Anid, anidulafungin; Caspo, caspofungin.

b

Reduced growth occurred, but the CLSI endpoint was not achieved.