FIG 1.

In vitro susceptibility to various aminoglycosides stratified by (A) amikacin (AMK) susceptibility, (B) gentamicin (GEN) susceptibility, and (C) tobramycin (TOB) susceptibility. P values denote differences in median MIC values of the respective aminoglycosides between the amikacin-, gentamicin-, and tobramycin-susceptible and -resistant isolates. The epidemiological cutoff was considered for amikacin resistance (MIC > 8 mg/liter). The MIC₅₀ and MIC₉₀ values are shown above the respective bars. PLZ, plazomicin.