TABLE 1.
In vitro susceptibility to different aminoglycosides of 346 Escherichia coli isolates in relation to the β-lactamase type produceda
| Aminoglycoside | ESBL (n = 302 isolates) |
AmpC (n = 44 isolates) |
||||||
|---|---|---|---|---|---|---|---|---|
| MIC50 (mg/liter) | MIC90 (mg/liter) | Range | No. (%) of resistant isolates | MIC50 (mg/liter) | MIC90 (mg/liter) | Range | No. (%) of resistant isolates | |
| Gentamicin | 1 | 64 | ≤0.125 to >64 | 86 (28.6) | 1 | 64 | 0.5 to >64 | 11 (25) |
| Tobramycin | 1 | 32 | ≤0.125 to >64 | 123 (40.9) | 1 | 8 | 0.5 to 32 | 12 (27.3) |
| Amikacin | 4 | 8 | 0.5 to >64 | 5 (1.7) | 2 | 4 | 2 to 8 | 0 |
| Plazomicin | 1 | 1 | 0.25 to 4 | NA | 1 | 1 | 0.5 to 2 | NA |
a
Resistance data were determined on the basis of EUCAST susceptibility breakpoints. NA, not applicable.