TABLE 1.
Druga | MIC/MEC (μg/ml)b |
|||
---|---|---|---|---|
Range | MIC50/MEC50 | MIC90/MEC90 | Geometric mean | |
AmB | 0.031 to 0.5 | 0.25 | 0.5 | 0.29 |
5-FC | 64 to >64 | 64 | 64 | 64 |
FLC | 4 to 64 | 16 | 64 | 25 |
ITC | 0.063 to 4 | 0.25 | 2 | 0.81 |
VRC | 0.063 to 4 | 0.25 | 2.00 | 0.89 |
POS | 0.031 to 0.5 | 0.125 | 0.50 | 0.20 |
MCZ | 0.125 to 1 | 0.50 | 1.00 | 0.57 |
KTZ | 0.125 to 1 | 0.50 | 1.00 | 0.52 |
AFG | 0.016 to 8 | 0.02 | 0.02 | 0.68 |
CAS | 0.25 to 1.00 | 0.5 | 1.00 | 0.60 |
GRZ | 0.05 to 2 | 0.63 | 2 | 0.92 |
TBF | 0.016 to 0.125 | 0.031 | 0.125 | 0.05 |
Abbreviations: AmB, amphotericin B; 5-FC, flucytosine; FLZ, fluconazole; ITC, itraconazole; VRC, voriconazole; POS, posaconazole; MCZ, miconazole; KTZ, ketoconazole; AFG, anidulafungin; CAS, caspofungin; GRZ, griseofulvin; TBF, terbinafine.
MECs were used for caspofungin and anidulafungin. MICs were used for all other drugs.