. Author manuscript; available in PMC: 2017 Jan 30.

Published in final edited form as: Ultrasound Obstet Gynecol. 2014 Jul;44(1):50–57. doi: 10.1002/uog.13287

Table 4.

One-way sensitivity analysis, varying the sensitivity of second-trimester ultrasound screening with four-chamber and outflow-tract views (4C + outflow) and the resulting incremental cost-effectiveness ratios (ICER) compared with the strategy involving a 4C+ outflow referred to a maternal–fetal medicine specialist (4C + outflow → MFM)

Sensitivity of 4C + outflow	ICER
Sensitivity of 4C + outflow	4C → MFM	4C → card	4C + outflow → card	MFM 4C + outflow → card	NT + outflow	Fetal echo
0.31	$3105	$2755	$919	$14079	$83346	$69822
0.42	$12604	$4385	$748	$16803	$86729	$79004
0.53	Dominated^*	$17 137	$660	$20912	$90962	$90994
0.64	Dominated^*	Dominated^*	$595	$27825	$95017	$107 319
0.75	Dominated^*	Dominated^*	$549	$41890	$99455	$130 843
0.86	Dominated^*	Dominated^*	$520	$86207	$104 355	$167 679

A strategy is dominated when it is more costly and less effective than the strategy to which it is being compared. 4C, four chamber; card, pediatric cardiologist; Fetal echo, fetal echocardiography; NT, nuchal translucency.