Table 4.
Measles antibody and cellular immunity measures after MMR vaccination, according to subject biological sex
| Immune measure | Male subjects (n=2,092) median (IQR)† |
Female subjects (n=780) median (IQR)† |
Adjusted p-value |
|---|---|---|---|
| Antibody titer, mIU/mLa | 834 (389–1,659) | 862 (419–1,737) | 0.89 |
| IFN-γ ELISPOT, SFU / 2×105PBMCsb |
14 (−5.67–30.7) | 18 (−7.33–42.1) | 0.623 |
a
Neutralizing antibody titer (mIU/mL), measured by the plaque reduction microneutralization assays (PRMN);
b
IFN-γ ELISPOT spot forming units (SFU), measured per 2 × 105 PBMCs (mean of measles virus-specific response, measured in triplicate wells, minus the mean of unstimulated response, also measured in triplicate wells)
†
Interquartile Range