FIG. 6.

Mitochondrial respiratory complex activity in GSNOR^−/− muscle. To test whether increased mitochondrial activity could contribute to the enhanced contractility of GSNOR^−/− tibialis anterior (TA) muscle, the specific activities and citrate synthase (activity)-normalized activities of mitochondrial respiratory chain complexes I, III, and IV were measured in wild-type (+/+) and GSNOR^−/− TA muscles. (A) Complex I-specific activity. (B) Citrate synthase activity (CS)-normalized complex I-specific activity. (C) Complex III-specific activity. (D) CS activity-normalized complex III-specific activity. (E) Complex IV-specific activity. (F) CS activity-normalized complex IV-specific activity. n = 6 for wild-type and GSNOR^−/− groups, respectively. n = 6 for all groups.