TABLE 3.

Characteristics of ongoing studies

Study name or title	Chief investigator	Study period (start and end dates) (country)	Study design	Participants	Intervention	Comparison	Outcomes
Pulmonary Rehabilitation and ACTIvity after COPD Exacerbations: the PRACTICE trial: a randomised trial [24]	R. Hughes	January 2015 to December 2016 (UK)	Parallel group, randomised pilot 2×2 trial	76 participants with clinically identified exacerbation of diagnosed COPD	1) In-hospital exercise training followed by in-home post-discharge early rehabilitation; 2) standard in-hospital care followed by in-home post-discharge early rehabilitation	1) In-hospital exercise training followed by standard discharge care; 2) standard in-hospital care followed by standard discharge	Subsequent uptake, adherence and completion of group-based community pulmonary rehabilitation
Video to Increase RehabiliTation Uptake following hospitalised Exacerbations of COPD (VIRTUE): a randomised controlled trial [25]	W. Man	January 2015 to January 2017 (UK)	Parallel group, randomised trial	200 adults aged >40 years diagnosed with COPD, admitted to hospital with acute exacerbation of COPD and fit enough to take part in pulmonary rehabilitation	Participants will be asked to watch a 5-min patient-designed video promoting early pulmonary rehabilitation plus usual care	Usual care: provided with standard verbal information and an A5 patient information leaflet about early pulmonary rehabilitation	Uptake, adherence and completion of post-exacerbation pulmonary rehabilitation
A tailored, psychological intervention for mild to moderate anxiety or depression in people with COPD: Tailored intervention for ANxiety and DEpression Management in COPD (TANDEM) [26]	S. Taylor	April 2016 to January 2021 (UK)	Three-phase study (phase I: preparation; phase II: pilot randomised controlled trial; phase III: a fully powered individually randomised controlled trial)	Adults with moderate–severe COPD with mild–moderate comorbid anxiety or depression and eligible for attendance at their local pulmonary rehabilitation; phase II: 45 participants; phase III: 430 participants	Tailored, one-to-one psychological intervention combined with practical problem-solving components based on: Self-management Programme of Activity Coping and Education (SPACE) and The Lung Manual, a nurse-led intervention based on cognitive behavioural principles and self-management, and developed to address mood disorders of anxiety in COPD; this psychological intervention links into, and interdigitates with, usual pulmonary rehabilitation, but is independent of it	Usual care: standard pulmonary rehabilitation without interdigitating psychological intervention	Uptake and completion of pulmonary rehabilitation (to be informed by the pre-pilot and pilot studies)

COPD: chronic obstructive pulmonary disease.