Fig 9. Competitive dynamics of T-targeting and D-targeting lineages.

Representative evolutionary trajectories of T (red curves) and D (blue curves) subpopulations are shown for the three regimes noted in Fig 8, one GC for each regime. Time evolution of mean affinity (A, C, E) and size (lower panel of B, D, F) of two subpopulations are presented, along with a history of encountered Ag for a typical B cell lineage in the winning subpopulation (upper panel of B, D, F). The actual affinity of T clones (solid blue curve in A, C, E) is bounded by the best and worst possible affinities (dashed blue curves in A, C, E).