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. 2017 Jan 30;12(1):e0170203. doi: 10.1371/journal.pone.0170203

Fig 2. PIC1 inhibition of MPO peroxidase activity in neutrophil lysate or purified MPO.

Fig 2

(A) Dose-response titration of PIC1 into a lysate of 106 neutrophils assaying MPO activity with TMB (n = 4). Data are means of independent experiments ±SEM. (B) PIC1 dose-response inhibition of pure MPO (80 nM) oxidation of TMB (n = 3). Data are means of independent experiments ±SEM. (C) PIC1 inhibition of pure MPO oxidation of ABTS and O-dianisidine. (D) Dose-response inhibition of pure MPO at various concentrations by PIC1 (n = 3). Data are means of independent experiments ±SEM.