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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: Neurobiol Aging. 2015 Oct 31;38:104–111. doi: 10.1016/j.neurobiolaging.2015.10.025

Table 1.

Demographic information

Variable CNnn CNnp CNpp p
N 115 16 26 N/A
Age in y at baseline scan (SD) 59.5 (8.77) 66.4 (8.67) 68.2 (6.3) <0.001
Gender (male/female) 35/80 5/11 10/16   0.73
Education in y (SD) 16.1 (2.4) 15.4 (2.5) 15.4 (2.4)   0.90
APOE ε4+ (% carriers)    23 (20)      9 (56)    17 (65) <0.001
MC SUVR at baseline (SD) 0.97 (0.07) 1.17 (0.10) 2.12 (0.60) <0.001
MC SUVR (follow-up) 1.02 (0.09) 1.47 (0.31) 2.48 (0.56) <0.001
MMSE at baseline 29.3 (0.86) 29.3 (1.09) 28.9 (1.51)   0.73
MMSE at follow-up 29.4 (0.92) 29.4 (0.96) 29.0 (1.42)   0.89
Follow-up time in y (SD) 3.30 (1.45) 3.26 (1.20) 2.99 (1.26)   0.37

Mean (standard deviation) or counts for demographic variables.

Key: APOE ε4, apolipoprotein E ε4 positive indicates at least one APOE ε4 allele; CNnn, cognitively normal individuals, PiB negative at both scans; CNnp, cognitively normal, PiB-negative at first scan but PiB positive at second scan; MC SUVR, mean cortical standard uptake volume ratio of PiB deposition; MMSE, Mini-Mental Status Examination; SD, standard deviation.