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. 2017 Jan 30;12(1):e0170914. doi: 10.1371/journal.pone.0170914

Fig 3. Resolution of poly(A) sites.

Fig 3

(A) Example of two overlapping candidate poly(A) sites supported in part (but not only) by alternative alignments of the same reads r1 and r2. (B) After calculation of evidence scores, both read r1 and r2 are assigned to the poly(A) site with higher evidence (site B). Poly(A) site A is discarded as it is no longer supported by any reads. Site B is supported by ≥ rs reads with distinct alignments starts and, thus, is included in the final ContextMap 2 output.