Skip to main content
. Author manuscript; available in PMC: 2017 Jan 30.
Published in final edited form as: Diabetes. 2016 Jul 8;65(10):3002–3007. doi: 10.2337/db16-0418

Figure 2.

Figure 2

Distributions of regression estimates resulting from leave-one-out permutation analysis. Solid line = estimate from main analysis (n=96 variants); dashed line = estimate with TCF7L2(rs7903146) removed; dotted line = estimate with FTO(rs1558902) removed.

A - Causal estimates (β coefficients) of BMI on type 2 diabetes estimated by an inverse-variance weighted method

B - Causal estimates (β coefficients) of BMI on type 2 diabetes estimated by MR-Egger

C - Causal estimates (β coefficients) of BMI on type 2 diabetes estimated by a weighted median method

D – Estimates of the intercept by MR-Egger