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. 2016 Dec 19;6(2):206–218. doi: 10.1016/j.molmet.2016.12.005

Figure 3.

Figure 3

Phosphorylation of IRS-1 and inflammatory markers. (A) Insulin receptor substrate 1 (IRS-1) serine 307 phosphorylation in liver and epididymal adipose tissue. (B–D) IRS-1 serine 307 phosphorylation densitometry in (B) liver, (C) adipose tissue, and (D) gastrocnemius muscle. (E) c-JunN-terminal kinase (JNK) phosphorylation in liver, epididymal adipose tissue, and gastrocnemius muscle. (F–H) JNK phosphorylation densitometry in (F) liver, (G) adipose, and (H) gastrocnemius muscle. *p < 0,05 vs. C57BL/6J HFD, ˆp < 0,05 vs. iNOS KO HFD. Bars represent mean +/− SEM from 4 to 8 mice. Similar results were observed when using delta percentage of baseline.