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. 2016 Dec 19;6(2):206–218. doi: 10.1016/j.molmet.2016.12.005

Figure 7.

Figure 7

Metabolic profile of C57BL/6J mice fed standard chow or a high-fat diet and treated with the ER stress blocker 4-phenyl butyric acid (PBA) and the iNOS inhibitor L-NIL. (A) Body weight, (B) epididymal fat mass, (C) fasting blood glucose, (D) insulin levels, and (E–F) glucose tolerance, measured by the 120 min glucose tolerance test in (E) the chow groups and (F) high fat diet groups, (G) Glucose utilization, as measured by euglycemic-hyperinsulinemic clamp. *p < 0.05 vs. C57BL/6J HFD, #p < 0.05 vs. C57BL/6J CHOW and ˆp < 0.05 C57BL/6J PBA/L-NIL HFD. Bars represent mean ± SEM from 4 to 8 mice.