Figure 3.
Inter-visit Weighted UniFrac distances associations with healing time for subjects that healed during the study. X axes represent the study visit; study visits were 2 weeks apart. (A) Inter-visit distances are shown for each subject and depict a negative trend over time. Line and point colors represent the number of study visits that the ulcer persisted (red = 1, green = 8). Ulcers stabilize at a rate of −0.024/visit, but start at a lower rate in those ulcers that require more time to heal (−0.036 per visit required to heal). (B) Inter-visit distances between baseline and first study visit as a function of number of visits until healing. A negative correlation is found even within this initial comparison (R2 = 0.1601, p<0.0001).